sente skin care

About Sente

The Senté brand is a privately held brand that was founded in San Diego, California in 2007. This innovative, specialty aesthetics company was born after a decade of researching the Heparan sulfate molecule. Research shows, it's an essential molecule that plays an important role in the skin's immune response to inflammation. The Heparan sulfate molecule belongs to water-binding molecules called glycosaminoglycan, this family also includes hyaluronic acid!

The research of this particular molecule is the foundation of the Sente brand as Sente is the first and only company to develop a low molecular weight version of Heparan Sulfate that can be infused into medical-grade skincare products.

This is a feat that this brand was able to successfully conquer and what birthed Sente's patented and proprietary Heparan Sulfate Analog Technology. A technology that replenishes depleted heparan sulfate levels, providing a natural increase to the skin’s immune response.

Sente continues to innovate and produce clinically proven and dermatologist-recommended products that deliver healthy-looking skin with minimal irritation. Sente understands that confidence in healthy skin is key and key ingredients used in formulations are what target and minimize skin concerns like skin inflammation, dry skin, for a range of skin tones and skin types.

Customer Reviews

"[DERMAL REPAIR CREAM] I bought this product because a good friend was using it and her skin looked fabulous. I love the texture and how a little goes a long way. After just a week of use I see improvements already." - Margret I., 9/11/2021

"[BIO COMPLETE SERUM] SO FAR SO GOOD!! As with any skincare product, time will tell. As of now, I notice it making my skin smoother and softer, and reducing redness. That’s a great start in my book. Little or no irritation each time I’ve applied it."- Kim O., 1/6/2022

Frequently Asked Questions

Where can I purchase Sente products?

Search our online store,, and shop for Sente products here! We are a proud authorized retailer and we only sell the best authentic Sente products on our site!

What does Senté’s heparan sulfate analog technology do?

Senté’s Heparan Sulfate Analog technology sinks deep into the skin's dermal layer to encourage and support the skin to naturally repair itself. As skin cells turnover this reduces signs of aging and minimizes the look of fine lines and wrinkles while promoting an even skin tone and texture.

Are products Sente cruelty-free?

There is no animal testing involved!

Are Sente products safe to use while pregnant or lactating?

It's recommended you consult your OB/GYN regarding the specific products you want to use during pregnancy or while breastfeeding.

Does Senté’s Bio Complete Serum cause breakouts?

This product is made with non-comedogenic ingredients that help prevent breakouts and clogged pores. Plus it's hydrating which helps minimize redness and irritation.

Is Sente medical grade?

Senté is a medical-grade skincare brand that is approved and recommended by academic organizations. The reason for this is, their products provide real and clinically shown results.

Who is Sente owned by?

 Sente has appointed Laurent Combredet as President and Chief Executive Officer

What are Sente's Best Sellers?

Sente Bio Complete Serum

This product is made with non-comedogenic ingredients that help prevent breakouts and clogged pores. Plus it's hydrating which helps minimize redness and irritation.

Sente Dermal repair cream 

It improves the appearance of skin texture and skin firmness. The deep hydration of the cream helps to diminish the appearance of fine lines and wrinkles and enhance skin tone for a more youthful radiance

Illuminé Eye Cream

Sente's Illumine Eye Cream improves hydration of the delicate skin around the eye area, minimizes the look of fine lines and wrinkles, and discoloration.

Neck firming cream

A deeply hydrating and firming cream designed to improve the neck and decollete area

Dermal contour pressed serum

A serum that is perfect for even the most sensitive skin supports the skin's natural ability to produce collagen and elastin for firmer, younger-looking.

Guaranteed Safe Checkout

Trust Seals